To calculate profit-loss for a given Cost and Sell Price.

 # Python Program to Calculate Profit or Loss

 
actual_cost = float(input(" Please Enter the Actual Product Price: "))
sale_amount = float(input(" Please Enter the Sales Amount: "))
 
if(actual_cost > sale_amount):
    amount = actual_cost - sale_amount
    print("Total Loss Amount = {0}".format(amount))
elif(sale_amount > actual_cost):
    amount = sale_amount - actual_cost
    print("Total Profit = {0}".format(amount))
else:
    print("No Profit No Loss!!!")

Python profit or loss output

 Please Enter the Actual Product Price: 1500
 Please Enter the Sales Amount: 1200
Total Loss Amount = 300.0